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RNA Interference

John Wiley & Sons
4.9/5 (10839 ratings)
Description:The 2006 Nobel Prize in Physiology or Medicine was awarded to Andrew Z. Fire and Craig C. Mello for their discovery of RNA interference (RNAi). RNAi is a biological process in which RNA molecules can silence (inhibit) or up- or down-regulate gene expression, typically by causing the destruction of specific messenger RNA (mRNA) molecules. This collection of articles begins with an introduction to RNAi, and proceeds to describe uses of this technology in various approaches to disease treatment, including gene therapy. Several laboratory protocols for silencing genes via RNAi are also provided, as are protocols for down-regulating and then rescuing those down-regulated genes, which demonstrates specificity of the approach.This e-book -- a curated collection from eLS, WIREs, and Current Protocols -- offers a fantastic introduction to the field of RNA interference for students or interdisciplinary collaborators.Table of Contents:IntroductionOverview of Gene Silencing by RNA Interference "Current Protocols in Nucleic Acid Chemistry"Daniel H. Kim, John J. RossiBiogenesis and function of endogenous and exogenous siRNAs "WIREs RNA"Nicholas M. Snead, John J. RossiTechniques & ApplicationsSmall Silencing RNAs and Gene Therapy "eLS"Dirk GrimmRNAi Screening: New Approaches, Understandings, and Organisms "WIREs RNA"Stephanie E. Mohr, Norbert PerrimonDelivery of RNAi mediators "WIREs RNA"Lance P. Ford, Masoud M. ToloueProtocolsSilencing of Gene Expression in Cultured Cells Using Small Interfering RNAs "Current Protocols in Cell Biology"Kumi Sakurai, Pritsana Chomchan, John J. RossiGene Down-Regulation with Short Hairpin RNAs and Validation of Specificity by Inducible Rescue in Mammalian Cells "Current Protocols in Cell Biology"Hoi Tang Ma, Randy Y.C. PoonWe have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with RNA Interference. To get started finding RNA Interference, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.
Pages
Format
PDF, EPUB & Kindle Edition
Publisher
Release
ISBN
1118829441

RNA Interference

John Wiley & Sons
4.4/5 (1290744 ratings)
Description: The 2006 Nobel Prize in Physiology or Medicine was awarded to Andrew Z. Fire and Craig C. Mello for their discovery of RNA interference (RNAi). RNAi is a biological process in which RNA molecules can silence (inhibit) or up- or down-regulate gene expression, typically by causing the destruction of specific messenger RNA (mRNA) molecules. This collection of articles begins with an introduction to RNAi, and proceeds to describe uses of this technology in various approaches to disease treatment, including gene therapy. Several laboratory protocols for silencing genes via RNAi are also provided, as are protocols for down-regulating and then rescuing those down-regulated genes, which demonstrates specificity of the approach.This e-book -- a curated collection from eLS, WIREs, and Current Protocols -- offers a fantastic introduction to the field of RNA interference for students or interdisciplinary collaborators.Table of Contents:IntroductionOverview of Gene Silencing by RNA Interference "Current Protocols in Nucleic Acid Chemistry"Daniel H. Kim, John J. RossiBiogenesis and function of endogenous and exogenous siRNAs "WIREs RNA"Nicholas M. Snead, John J. RossiTechniques & ApplicationsSmall Silencing RNAs and Gene Therapy "eLS"Dirk GrimmRNAi Screening: New Approaches, Understandings, and Organisms "WIREs RNA"Stephanie E. Mohr, Norbert PerrimonDelivery of RNAi mediators "WIREs RNA"Lance P. Ford, Masoud M. ToloueProtocolsSilencing of Gene Expression in Cultured Cells Using Small Interfering RNAs "Current Protocols in Cell Biology"Kumi Sakurai, Pritsana Chomchan, John J. RossiGene Down-Regulation with Short Hairpin RNAs and Validation of Specificity by Inducible Rescue in Mammalian Cells "Current Protocols in Cell Biology"Hoi Tang Ma, Randy Y.C. PoonWe have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with RNA Interference. To get started finding RNA Interference, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.
Pages
Format
PDF, EPUB & Kindle Edition
Publisher
Release
ISBN
1118829441
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