Read Fragment-Based Drug Design: Tools, Practical Approaches, and Examples

Fragment-Based Drug Design: Tools, Practical Approaches, and Examples

Lawrence C. Kuo

4.9/5 (26235 ratings)

Description:There are numerous excellent reviews on Fragment Based Drug Discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits. Offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Fragment-Based Drug Design: Tools, Practical Approaches, and Examples. To get started finding Fragment-Based Drug Design: Tools, Practical Approaches, and Examples, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

Pages: —

Format: PDF, EPUB & Kindle Edition

Publisher: —

Release: —

ISBN: 0123812755

Description: There are numerous excellent reviews on Fragment Based Drug Discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits. Offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Fragment-Based Drug Design: Tools, Practical Approaches, and Examples. To get started finding Fragment-Based Drug Design: Tools, Practical Approaches, and Examples, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

Special Offer | $0.00

Special Offer! | $0.00

Fragment-Based Drug Design: Tools, Practical Approaches, and Examples

Fragment-Based Drug Design: Tools, Practical Approaches, and Examples

More Books

Fragment Based Drug Design: Tools, Practical Approaches, and Examples (Volume 493) (Methods in Enzymology, Volume 493)

Fragment Based Drug Design: Tools, Practical Approaches, and Examples (Volume 493) (Methods in Enzymology, Volume 493)

Digital Control Systems

Digital Control Systems

Prostaglandins, Platelets, Lipids: New Developments in Atherosclerosis

Prostaglandins, Platelets, Lipids: New Developments in Atherosclerosis

Fragment Based Drug Design: Tools, Practical Approaches, and Examples (ISSN Book 493)

Fragment Based Drug Design: Tools, Practical Approaches, and Examples (ISSN Book 493)

Methods in Enzymology, Volume 275: Viral Polymerases and Related Proteins

Methods in Enzymology, Volume 275: Viral Polymerases and Related Proteins

Internet in Singapore

Internet in Singapore

Phospholipids and Cellular Regulation: 001

Phospholipids and Cellular Regulation: 001

Recent Advances in Spray Combustion: Spray Combustion Measurements and Model Simulation (Progress in Astronautics & Aeronautics)

Recent Advances in Spray Combustion: Spray Combustion Measurements and Model Simulation (Progress in Astronautics & Aeronautics)

Media, Communication and Society: An Asian Reader

Media, Communication and Society: An Asian Reader