Read Division of Cancer Biology and Diagnosis, Vol. 2: Annual Report, October 1, 1984 Through September 30, 1985 (Classic Reprint)

Division of Cancer Biology and Diagnosis, Vol. 2: Annual Report, October 1, 1984 Through September 30, 1985 (Classic Reprint)

U.S. National Cancer Institute

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Description:Excerpt from Division of Cancer Biology and Diagnosis, Vol. 2: Annual Report, October 1, 1984 Through September 30, 1985 Within the Tumor Biology Program, there are three major areas of investigation which conveniently correspond to different theories of how to control the development and progression of neoplastic disease. The first is understanding the basic biochemical mechanisms involved in growth control, whether these involve particular external signals that initiate the process of cell division or cellular molecules more directly responsible for the control of dna replication and metabolism. This kind of information can lead to the development of specific hormonal and drug therapies. The second is studying changes that occur at the molecular level which lead to cancer cell invasion. The invasive behavior of cancer cells is a prerequisite to malignancy, or the ability of tumors to invade surrounding tissues, escape normal host defense mechanisms and become established at multiple secondary metastatic sites of growth. Theoretically, if the invasive properties of malignant tumors can be controlled and these tumors confined to particular sites, metastasis, the major killer in cancer patients, will not occur. Treatment of tumors confined to a single site is usually more successful. The third is to develop detailed biological and biochemical information about the processes which induce cancer cell differentiation. There is good reason to believe that many kinds of cancers will respond to external stimuli and differentiate. If the genetic program of an actively growing cancer could be changed to one of terminal differentiation, then the malignant tumor could be rendered harmless. Although the above emphasis of the the Tumor Biology Program in the areas of growth, in vasion and differentiation is stated in simple terms, they provide a purposeful way of viewing the role of basic biological research to the ultimate goal of curing cancer. The kinds of information developed in the Tumor Biology Program provide a foundation for and relate directly or indirectly to nearly every other program area within the National Cancer Institute. The importance of basic tumor biology research to the National Cancer Plan is reflected by the large million commitment of the nci to this program area in FY 1985. (see Budget Table.) Complete listings and summaries of all grants supported by the Tumor Biology Program are included in the attached Appendices. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Division of Cancer Biology and Diagnosis, Vol. 2: Annual Report, October 1, 1984 Through September 30, 1985 (Classic Reprint). To get started finding Division of Cancer Biology and Diagnosis, Vol. 2: Annual Report, October 1, 1984 Through September 30, 1985 (Classic Reprint), you are right to find our website which has a comprehensive collection of manuals listed.
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Description: Excerpt from Division of Cancer Biology and Diagnosis, Vol. 2: Annual Report, October 1, 1984 Through September 30, 1985 Within the Tumor Biology Program, there are three major areas of investigation which conveniently correspond to different theories of how to control the development and progression of neoplastic disease. The first is understanding the basic biochemical mechanisms involved in growth control, whether these involve particular external signals that initiate the process of cell division or cellular molecules more directly responsible for the control of dna replication and metabolism. This kind of information can lead to the development of specific hormonal and drug therapies. The second is studying changes that occur at the molecular level which lead to cancer cell invasion. The invasive behavior of cancer cells is a prerequisite to malignancy, or the ability of tumors to invade surrounding tissues, escape normal host defense mechanisms and become established at multiple secondary metastatic sites of growth. Theoretically, if the invasive properties of malignant tumors can be controlled and these tumors confined to particular sites, metastasis, the major killer in cancer patients, will not occur. Treatment of tumors confined to a single site is usually more successful. The third is to develop detailed biological and biochemical information about the processes which induce cancer cell differentiation. There is good reason to believe that many kinds of cancers will respond to external stimuli and differentiate. If the genetic program of an actively growing cancer could be changed to one of terminal differentiation, then the malignant tumor could be rendered harmless. Although the above emphasis of the the Tumor Biology Program in the areas of growth, in vasion and differentiation is stated in simple terms, they provide a purposeful way of viewing the role of basic biological research to the ultimate goal of curing cancer. The kinds of information developed in the Tumor Biology Program provide a foundation for and relate directly or indirectly to nearly every other program area within the National Cancer Institute. The importance of basic tumor biology research to the National Cancer Plan is reflected by the large million commitment of the nci to this program area in FY 1985. (see Budget Table.) Complete listings and summaries of all grants supported by the Tumor Biology Program are included in the attached Appendices. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Division of Cancer Biology and Diagnosis, Vol. 2: Annual Report, October 1, 1984 Through September 30, 1985 (Classic Reprint). To get started finding Division of Cancer Biology and Diagnosis, Vol. 2: Annual Report, October 1, 1984 Through September 30, 1985 (Classic Reprint), you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

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Division of Cancer Biology and Diagnosis, Vol. 2: Annual Report, October 1, 1984 Through September 30, 1985 (Classic Reprint)

Division of Cancer Biology and Diagnosis, Vol. 2: Annual Report, October 1, 1984 Through September 30, 1985 (Classic Reprint)

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