Description:The riveting account of a community from the remote mountains of Colombia whose rare and fatal genetic mutation is unlocking the secrets of Alzheimer’s diseaseIn the 1980s, a neurologist named Francisco Lopera traveled on horseback into the mountains seeking families with symptoms of dementia. For centuries, residents of certain villages near Medellín had suffered memory loss as they reached middle age, going on to die in their fifties. Lopera discovered that a unique genetic mutation was causing their rare hereditary form of early onset Alzheimer’s disease. Over the next forty years of working with the “paisa mutation” kindred, he went on to build a world-class research program in a region beset by violence and poverty.In Valley of Forgetting, Jennie Erin Smith brings readers into the clinic, the laboratories, and the Medellín trial center where Lopera’s patients receive an experimental drug to see if Alzheimer’s can be averted. She chronicles the lives of people who care for sick parents, spouses, and siblings, all while struggling to keep their own dreams afloat. These Colombian families have donated hundreds of their loved ones’ brains to science and subjected themselves to invasive testing to help uncover how Alzheimer’s develops and whether it can be stopped. Findings from this unprecedented effort could hold the key to understanding and treating the disease, though it is unclear what, if anything, the families will receive in return.Smith’s immersive storytelling brings this complex drama to life, inviting readers on a scientific journey that is as deeply moving as it is engrossing.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Valley of Forgetting: Alzheimer's Families and the Search for a Cure. To get started finding Valley of Forgetting: Alzheimer's Families and the Search for a Cure, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.
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0525536094
Valley of Forgetting: Alzheimer's Families and the Search for a Cure
Description: The riveting account of a community from the remote mountains of Colombia whose rare and fatal genetic mutation is unlocking the secrets of Alzheimer’s diseaseIn the 1980s, a neurologist named Francisco Lopera traveled on horseback into the mountains seeking families with symptoms of dementia. For centuries, residents of certain villages near Medellín had suffered memory loss as they reached middle age, going on to die in their fifties. Lopera discovered that a unique genetic mutation was causing their rare hereditary form of early onset Alzheimer’s disease. Over the next forty years of working with the “paisa mutation” kindred, he went on to build a world-class research program in a region beset by violence and poverty.In Valley of Forgetting, Jennie Erin Smith brings readers into the clinic, the laboratories, and the Medellín trial center where Lopera’s patients receive an experimental drug to see if Alzheimer’s can be averted. She chronicles the lives of people who care for sick parents, spouses, and siblings, all while struggling to keep their own dreams afloat. These Colombian families have donated hundreds of their loved ones’ brains to science and subjected themselves to invasive testing to help uncover how Alzheimer’s develops and whether it can be stopped. Findings from this unprecedented effort could hold the key to understanding and treating the disease, though it is unclear what, if anything, the families will receive in return.Smith’s immersive storytelling brings this complex drama to life, inviting readers on a scientific journey that is as deeply moving as it is engrossing.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Valley of Forgetting: Alzheimer's Families and the Search for a Cure. To get started finding Valley of Forgetting: Alzheimer's Families and the Search for a Cure, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.