Description:Chapters: Vladimir of Novgorod, Haemophilia in European Royalty, Battenberg Family, Prince Christian, Sadije Toptani, Franco, Esdron, Emperor-Elect. Source: Wikipedia. Pages: 40. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Haemophilia figured prominently in the history of European royalty in the 19th and 20th centuries. Queen Victoria, through two of her five daughters (Princess Alice of the United Kingdom and Princess Beatrice of the United Kingdom), passed the mutation to various royal houses across the continent, including the royal families of Spain, Germany and Russia. Victoria's son Leopold suffered from the disease. For this reason, haemophilia was once popularly called "the royal disease." The sex-linked X chromosome disorder manifests almost entirely in males, although the gene for the disorder is inherited from the mother. However females carrying the faulty X chromosome can pass the chromosome to their descendents. Expression of the disorder is more common in males due to the fact that females have two X chromosomes while the male only has one. If a male's X chromosome is defective, there is not another to mask the disorder. In about 30% of cases, however, there is no family history of the disorder and the condition is the result of a spontaneous gene mutation. Victoria appears to have been a spontaneous or de novo mutation, and is considered the source of this line of the disease. Her mother, Victoria, was not known to have a family history of the disease. Descendants of Victoria's maternal half-sister, Feodora, are not known to have suffered from the disease. Queen Victoria's father, Edward, was not a haemophiliac and the probability of her mother having had a lover who suffered from haemophilia is minuscule, primarily due to the low life expectancy of 19th century haemop...More: http: //booksllc.net/?id=431020We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with European Royalty: Vladimir of Novgorod, Haemophilia in European Royalty, Battenberg Family, Prince Christian, Sadije Toptani, Franco, Esdron. To get started finding European Royalty: Vladimir of Novgorod, Haemophilia in European Royalty, Battenberg Family, Prince Christian, Sadije Toptani, Franco, Esdron, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.
Pages
42
Format
PDF, EPUB & Kindle Edition
Publisher
Books LLC
Release
2010
ISBN
1157554997
European Royalty: Vladimir of Novgorod, Haemophilia in European Royalty, Battenberg Family, Prince Christian, Sadije Toptani, Franco, Esdron
Description: Chapters: Vladimir of Novgorod, Haemophilia in European Royalty, Battenberg Family, Prince Christian, Sadije Toptani, Franco, Esdron, Emperor-Elect. Source: Wikipedia. Pages: 40. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Haemophilia figured prominently in the history of European royalty in the 19th and 20th centuries. Queen Victoria, through two of her five daughters (Princess Alice of the United Kingdom and Princess Beatrice of the United Kingdom), passed the mutation to various royal houses across the continent, including the royal families of Spain, Germany and Russia. Victoria's son Leopold suffered from the disease. For this reason, haemophilia was once popularly called "the royal disease." The sex-linked X chromosome disorder manifests almost entirely in males, although the gene for the disorder is inherited from the mother. However females carrying the faulty X chromosome can pass the chromosome to their descendents. Expression of the disorder is more common in males due to the fact that females have two X chromosomes while the male only has one. If a male's X chromosome is defective, there is not another to mask the disorder. In about 30% of cases, however, there is no family history of the disorder and the condition is the result of a spontaneous gene mutation. Victoria appears to have been a spontaneous or de novo mutation, and is considered the source of this line of the disease. Her mother, Victoria, was not known to have a family history of the disease. Descendants of Victoria's maternal half-sister, Feodora, are not known to have suffered from the disease. Queen Victoria's father, Edward, was not a haemophiliac and the probability of her mother having had a lover who suffered from haemophilia is minuscule, primarily due to the low life expectancy of 19th century haemop...More: http: //booksllc.net/?id=431020We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with European Royalty: Vladimir of Novgorod, Haemophilia in European Royalty, Battenberg Family, Prince Christian, Sadije Toptani, Franco, Esdron. To get started finding European Royalty: Vladimir of Novgorod, Haemophilia in European Royalty, Battenberg Family, Prince Christian, Sadije Toptani, Franco, Esdron, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.